telomerase activation meaning in Chinese
端粒酶活性
Examples
- We summarize the dual role of telomeres in cancer , and the relationship between telomerase activation and tumours
笔者综述了端粒的缩短所扮演的双重角色，以及端粒酶的激活与肿瘤之间的关系。 - Telomerase is a new target of oncotherapy , the growth of tumor could be repressed by restraining telomerase activation
端粒酶已成为新的肿瘤标志物及肿瘤治疗的新靶点，抑制肿瘤细胞端粒酶活性可望达到抑制肿瘤生长的目的。 - When mms was added directly to s . cerevisiae s288c cell extracts immediately before primer addition , telomerase activity remained unchanged . thus , a direct influence of mms on trap assay does not seem to be involved in telomerase activation observed after drug treatment
如果在加人引物之前将mms直接加在酿酒酵母5288c细胞蛋白提取物zh ，结果显示端粒酶活性没有变化，因此排除了mms对端粒酶的直接激活作用。 - Comparison of telomerase activity in a few cell lines showed that application of dna sequencer in detecting telomerase enzyme activity is applicable in quantitative and qualitative determination of telomerase activity . the result of this method could be available within 4 - 5 hours with high sensitivity and less handling time . it provided a reliable means to study on regulative mechanism of telomerase activity and relationship between telomerase activation and malignancy
Trap与dna测序相结合检测端粒酶活性的方法，操作简便、快速、经济、无放射性危害，可在3 ? 4小时内得到检测结果，大大缩短了检测时间，为研究端粒酶活性的调节机制、端粒酶与恶性肿瘤之间的关系以及临床上鉴别和诊断肿瘤的良恶性提供了一种检测手段。 - Telomerase is a celler reverse transcriptase which catalyzes the synthesis and extension of telomeric dna . telomerase activation is not observed in normal tissues of somatic origin but in almost 90 % of human cancer , with the result the telomere shorten progressively with cell division and thus is a critical step for multistep carcinogenesis
正常人体细胞(非生殖细胞)中端粒酶活性的表达很低，或用目前的方法几乎检测不到，而在90以上的恶性肿瘤中可检测到端粒酶活性，相应的良性肿瘤则为阴性或仅有少数阳性。